A New Triterpenoid Saponin and Two Neolignans from Ligularia veitchiana
نویسندگان
چکیده
Phytochemical investigation of the rhizomes and roots of Ligularia veitchiana afforded a new triterpenoid saponin and two known neolignans named liguveitoside B (1), citrusin A (2) and citrusin B (3), respectively. This is the first demonstration of the occurrence of a 8-O-4’ neolignan and the second report on the isolation of triterpenoid saponin in the genus Ligularia. Their structures were elucidated on the basis of spectral data, particularly HSQC, HMBC and NOE experiments. Compound 1 exhibited weak cytotoxicity against a human acute promyelocytic leukemia cell-line (HL-60).
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